A new product for dyslipidemia
Useful to reduce total cholesterol, LDL, apolipoproteins B and triglycerides.

Mixture of Polycosanols, Polymethoxylated flavones, Tocotrienols, Chromium Polynicotinate and Astaxantine.

Pack size: capsules of 390 mg each
Useful as an adjuvant to the diet in the treatment of hyperlipidemia as it helps to control cholesterol and tryglicerides.
It can be used in association with statins according to medical advice.

Components

Miracol is a mixture of the most studied and efficacious natural products that, thanks to their synergy, reduce LDL cholesterol and the formation of ApoB (precursor of LDL), without any side effects that can be caused instead by traditional lipid-lowering statin drugs.

Polymethoxylated Flavones
Class of flavonoids polymethoxylated, obtained by the peel of citrus fruit, with antioxidant and anti-inflammatory action and with a more efficacious lipid- lowering action than other flavonoids.
The two main components are Nobiletin and Tangeretin.
Nobiletin
Beyond the lipid-lowering action, it also inhibits the formation of foam cells on the vascular wall.
Tangeretina
Beyond the lipid-lowering action, it also acts on two steps of the byosinthetic pathway that lead to the formation of ApoB and tryglicerides.

Polycosanols
Are extracted from cane sugar. Many studies show the effectiveness of Polycosanols, with a proper daily intake, in reducing cholesterolemia. High dosage is also well tolerated. Clinical trials exclude hepatic side effects.

Chromium Polynicotinate
Constituted by the association of Cr trivalent and nicotinic acid. A lack of chromium can lead to insulin resistance. Recent research has shown that a compound with 0.2mg of chromium bound to niacin in complex (only 200 mg) has produced significant results against hypercholesterolemia. The key factor of this action could be the efficacy of chromium in enhancing the insulin action.

Tocotrienols
Powerful antioxidants found in many plants. Improve the action of the polymethoxylated flavones, have an antioxidant and anti-inflammatory action with a strong lipid-lowering action.

Astaxantine
Carotenoid extremely common in the sea world, extracted from the microalgae Haematococcus pluvialis; it is responsible for the typical pinkish colour of some fish (e.g. salmon) and of most shellfish. Is recognized by science as the most powerful antioxidant.

Dosage

1 capsule daily, preferably in the evening.

GLUTEN AND LACTOSE FREE

Bibliography

A.F.G. Cicero, M. Bove, B. Gerocarni, M. Giovannini, C. Borghi – “Evaluation of the short term efficacy and tolerability af a combined nutraceutical with lipid-lowerin properties:a randomized clinical trial” – Dept. of internal medicine, aging and nephrological diseases, University of Bologna, Italy. Mediterranean Journal Nutrition Metabolism 2011

Castano G, Mas R, Fernandez L et al (2000) – “Effects of policosanol on postmenopausal women with type II hypercholesterolemia” – Gynecol Endocrinol 14(3):187-195

R.M. Hackman – “Chromium and Cholesterol” – Dept. of Nutrition and Human Performance – University of Oregon, Eugene

Kurowska EM, Manthey JA – “Hypolipidemic effects and absorption of citrus polymethoxylated flavones in hamsters with diet-induced hypercholesterolemia.” – J Agric Food Chem. 2004 May 19;52(10):2879-86

Qureshi AA, Sami SA, Sasler WA, Khan FA – “Dose-dependent suppression of serum cholesterol by tocotrienol-rich fraction (TRF25) of rice bran in hypercholesterolemic humans.” – Real Natural Remedies. Atherosclerosis. 2002 Mar;1161(1):199-207

Elzbieta M. Kurowska, Jhon A. Manthey, Adele Casaschi and Andre G. Theriault – “Modulation of HepG” Cell Net Apolipoprotein B Secretion by the Citrus Polymethoxyflavone, Tangeretin.- Lipids, Vol. 39, no. 2 (2004)

Asaf A Qureshi, Nilofer Qureshi, Judith O Hasler-Rapacz, Frank E Weber, Venod Chaudhary, Thomas D Crenshaw, Abdul Gapor, Augustine SH Ong, Yoon H Chong, David Peterson and Jan Rapacz - “Dietary tocotrienols reduce concentrations of plasma cholesterol, apolipoprotein B, thromboxane B2, and platelet factor 4 in pigs with inherited hyperlipidemias. – The American Journal of Clinical Nutrition 1991;53:1042S-6S